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Showing posts with label becomes. Show all posts
Showing posts with label becomes. Show all posts

Thursday, November 7, 2013

Lexus IS 300h Becomes Rolling Artist | Edmunds.com

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A Lexus IS 300h paints portraits in the new Art Is Motion campaign. | November 01, 2013 | Toyota Motor Sales, U.S.A., Inc.

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Just the Facts:Lexus Belgium has launched the Art Is Motion campaign, in which a one-off IS 300h hybrid can paint the driver's portrait.Sensors in the car monitor inputs like speed and acceleration, and a computer turns the data into "digital brush strokes."The Lexus IS 300h, even one that doesn't paint, is not currently available in the U.S.

BRUSSELS, Belgium — Lexus Belgium has launched its new Art Is Motion campaign, in which drivers of a specially equipped IS 300h hybrid sedan can have their portrait painted by the car itself.

Always wanted to be an artist, but can't draw a straight line? Couldn't even manage to "Draw This Clown" for mail-order art classes? No worries. Thanks to Lexus, anyone who can drive a car can "paint" a self-portrait.

With Art Is Motion, created by the Happiness Brussels agency, the car does the hard part by measuring a person's driving style and turning it into what Lexus calls "digital brush strokes."

The resulting portrait is projected onto the in-car multimedia screen and constantly evolves as the car is driven. Eventually, the finished image is sent to a dedicated Web site where it can then be viewed publicly.

Currently, the Art Is Motion site features images of art collector Walter Vanhaerent, who served as the test subject for the project. Recordings of some of his trips are available there in two-minute video clips that show the portraits as they are being created.

The style of the painting comes from Spanish artist Sergio Albiac, known for his innovative blending of art and science. For example, he recently combined Hubble telescope images with user input from social media outlets to create more than 1,000 computer-generated "stardust portraits."

In the Art Is Motion project, the creative process begins with a digital photograph of the driver. As various sensors monitor such inputs as speed, acceleration and the balance of use between the hybrid's gas and electric power plants, an onboard computer converts the data into colors and shapes.

Lexus says that spirited driving results in lots of bold red hues and strong brush strokes, while cruising quietly in electric mode renders softer strokes in cool shades of blue.

Unfortunately, the IS 300h is currently only available in Europe and Japan, and Lexus has announced no plans to bring it to the U.S. in the immediate future. And since, at the moment, there is only a single Art Is Motion car, American Lexus fans who are also frustrated artists are out of luck on both counts.

Enthusiasts in Europe, however, can participate in an auction for the one-off portrait-painting hybrid on the Art Is Motion Web site.

As Vincent van Gogh once said: "Art, although produced by man's hands, is something not created by hands alone, but something which wells up from a deeper source out of our soul." Or, in this case, from an onboard computer algorithm.

Edmunds says: We're with Vinny on that soul thing.

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Wednesday, July 18, 2012

Pill of progress: what are the chances of a drug becomes for the market?

The following is a guest post by Chad Parmet, a research associate with the Foundation for informed medical decisions.  Chad meets, assesses and summarizes the current medical research to support decision-making programs shared ® new or revised. Prior to joining the Foundation, he worked as a medical writer. He holds a Bachelor's degree in physics from the University of Pennsylvania. In the past, he revised many stories to HealthNewsReview.org. (Foundation is funding this project, but has no control over what is published here).


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Many times I read that researchers have cooked some new wonder drug that will change the world. But many of these miracles never materialised. That is why one of the criteria HealthNewsReview.org rates articles on if they ever set appropriate expectations about the availability of the hot new thing.


But what should be a drug that is still being tested our expectations?


A compound can do it in a prescription, it must run a gauntlet of studies in animals and humans. FDA analyzes the results and decide whether to approve it for use in Americans.


So I've been thinking: what are the chances that a drug in the midst of this challenge, generating headlines along the way, will never make it our medicine cabinets?


I poked around Google, PubMed and trip to evidence about these probabilities. Haven't seen any meta-analyses. I found a series of studies that used different estimates to produce chances. Clearly, I can't make a reliable estimate of the odds without finding a solid, systematic meta-analysis of studies of high quality. That said, the estimates were at the same level. And the stadium was interesting.


The chart below is my "essence" of the results of the recent, reviewed studies that — in my opinion — were more generalizable to small-molecule drugs that seek their first indications of the FDA.


The odds that a drug to each phase of the research
will eventually make it to the market


 

The essence of Adams Bratner & Davis et al 2006, 2011, DiMasi et al 2010, Kola & Landis 2004 and Paul et al 2010


Here are some important caveats about these numbers:


I could go. This is not an academic study, just an exercise.


With these limitations in mind, the true essence of exercise is that I take experimental drugs seem to have a lower likelihood of doing so on the market than what one would expect from the revolutionary tone used in typical news coverage next miracle drug.


I would love to know if there is a formal meta-analysis or a summary of the best literature, that I missed. If you know of one, please leave a comment below.


Chad Parmet

Disclaimer: all searches and conclusions are my own and do not represent the views and opinions of my employer, the basis of informed medical decisions.