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Sunday, November 10, 2013

Detroit 3 Report Double-Digit Sales Gains in October | Edmunds.com

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Sales of the 2014 Chevrolet Silverado and GMC Sierra increased 62 percent from September 2013. | November 01, 2013 | General Motors Corporation

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Just the Facts:The government shutdown did not put the brakes on October car sales as the Detroit 3 reported double-digit gains on Friday.General Motors said its U.S. sales were up 16 percent in October, while Chrysler reported an 11 percent sales increase.Ford said sales rose 14 percent on the strength of its F-Series trucks, Ford Fusion and Fiesta.

DETROIT — The government shutdown did not put the brakes on October car sales as the Detroit 3 reported double-digit gains on Friday.

"Once again, the U.S. car buyer proved to be stunningly resilient," said Michelle Krebs, Edmunds senior analyst. "Indeed, car sales slowed during the two-week government shutdown, but picked up once again when the shutdown ended."

General Motors said its U.S. sales were up 16 percent in October with 226,402 vehicles delivered.

"The sales tempo really picked up after the government shutdown ended," said Kurt McNeil, vice president of GM's U.S. sales operations, in a statement. "We are particularly pleased with our truck momentum."

Sales of the 2014 Chevrolet Silverado and GMC Sierra increased 62 percent from September 2013.

Chrysler reported an 11 percent sales increase with U.S. sales of 140,083 vehicles. The 2014 Jeep Cherokee went on sale in October, recording sales of 579 units in its partial month of sales. The Dodge Durango was a strong performer with a 59 percent increase.

The Durango is the subject of a new advertising campaign starring Will Ferrell as goofy news anchor Ron Burgundy.

"After a choppy start to the beginning of the month, Chrysler Group sales accelerated in the second half of the month with renewed consumer confidence and the launch of our all-new Jeep Cherokee," said Reid Bigland, Chrysler head of U.S. sales, in a statement.

Ford said sales rose 14 percent on the strength of its F-Series trucks, Ford Fusion and Fiesta. The Lincoln brand posted an overall increase of 38 percent, largely due to the 2014 Lincoln MKZ. Ford recorded total U.S. sales of 191,985 vehicles.

Hyundai reported an October sales increase of 7 percent, due to strong sales of the 2014 Hyundai Santa Fe, Sonata and Equus.

"Post-shutdown rebound drives record 53,555," tweeted John Krafcik, Hyundai Motor America CEO.

Nissan was up 14 percent in October. Volkswagen of America was a bleak spot in the monthly report, with 28,129 vehicles delivered in October for a drop of 18 percent.

Edmunds says: Bad news out of Washington did little to stop sales for most automakers.

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Monday, July 8, 2013

How to Recognize and Report Child and Elder Abuse

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Child and elder abuse is a serious problem that affects people from all walks of life. One of the most important ways to protect victims from abuse is by making sure they get the help they need and by reporting cases to the authorities.

Here’s how to recognize the different types of abuse and what to do in case you know someone who is a victim.

Children who are victims of physical or emotional abuse often display mental and social development problems. In most cases, the abuse comes from their own parents or caretakers. Below are some of the signs of abuse:

Physical abuse: A child who suffers from physical abuse might have bruises, burn marks, fractures and scars. They are often fearful of adults or certain people.Sexual abuse: Victims of sexual abuse are forced to have sexual relations or engage in inappropriate physical contact with adults. One sign of sexual abuse is feeling uncomfortable when changing clothes.Emotional abuse: Children who experience emotional abuse are often victims of private or public humiliation and neglect. A child who is a victim might show sudden changes in behavior and act violently.Neglect: Children who are physically neglected show signs of lack of personal hygiene and bad health due to malnutrition, among other things.

If you know or suspect that a child is a victim of abuse and is in immediate danger, call 911. To report a case of child abuse, call the National Child Abuse Hotline at 1-800-422-4453. ChildWelfare.gov also has information on how to report suspected child maltreatment as well as other resources for victims.

Elder abuse can occur in the victim’s home or at places like assisted living facilities. People who abuse the elderly are usually people who know or take care of the victims. There are several types of abuse and all of them can have a profound negative impact on a person’s physical and mental health.

Physical abuse: As with child abuse, elders who suffer from physical abuse also might show bruises or other signs of injury on their bodies. They might often act fearful or look intimidated.Sexual abuse: Elders who suffer from sexual abuse might become withdrawn.Emotional abuse: This occurs when the victim is humiliated and treated with disrespect. The victim might feel useless or inferior and might suffer from depression.Neglect: Elders show signs of physical neglect when caretakers fail to help them with their personal hygiene, food, clothing and medications.Financial abuse: Elders are often targets of financial fraud. This usually happens when people who take care of elders steal their retirement or Social Security money.

If you know or suspect an elder is a victim of abuse and is in immediate danger, call 911. To report a case of elder abuse, call 1-800-677-1116 or visit the National Center on Elder Abuse Abuse where you can find more information on how to help victims.

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Tuesday, July 2, 2013

Get Your Free Credit Report

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By law, you are entitled to receive one FREE copy of your credit report per year, from each credit agency. Find out how to get your report.

We welcome your comments if you are 13 or older, and hope that our conversations here will be polite. You are responsible for the content of your comments.

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Business Tax Working Group final report on the tax treatment of losses - 13 April 2012

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Friday, June 14, 2013

What is the difference between counting all today plugin Google analytics report?

So this is a super fun, so I'll get right to the ...

We had a cluster failure today we need to return back from 2 weeks (May 16, 2013).

That means anything done between 16 May and 1 June is gone.

More information can be found here.


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Wednesday, June 12, 2013

The Media Equation: Despite Report of Her Firing, Nikki Finke Is Still Standing

Anybody who has read Nikki Finke’s Deadline Hollywood, an industry Web site, has seen this kind of public execution. It is a specialty of hers, often backed up by a force field that makes it come true regardless of whether it was to begin with.

Except this time the article was written by Sharon Waxman, who runs The Wrap, a competing Web site, and the person who was reportedly being given the gate was none other than Nikki Finke.

“Nikki Finke has been fired from the blog she founded, Deadline Hollywood, and will be leaving the company as soon as this week, multiple individuals with knowledge of the situation have told me,” Ms. Waxman wrote on Sunday, June 2.

But the news was not followed by the sound of Champagne corks popping in the executive suites Ms. Finke had routinely terrorized for one simple reason: it did not turn out to be true. Ms. Waxman, perhaps driven by wish fulfillment, wrote beyond the facts at hand.

Still, the town is enjoying the moment, watching a knife fight between two industry observers and former pals who clearly can’t stand each other. Ms. Finke has the upper hand, with a closely followed site and a long reputation for breaking important industry news, while Ms. Waxman, whose site has struggled, is clearly punching up.

Ms. Waxman’s decision to begin publishing The Wrap in 2009, with backing from Howard Schultz, the chief executive of Starbucks, was viewed by Ms. Finke as an act of betrayal. The sniping has been remarkable, even by Hollywood standards, but the story of Ms. Finke being fired represented a huge escalation.

There is irony in the moment because Ms. Finke is the queen of the ritual sacrifice, having roasted industry leaders like Marc Shmuger of Universal and Ben Silverman of NBC until they caught fire and ended up out of their jobs.

Ms. Finke is erratic but very effective, using old-school tactics to power a new media enterprise. She and her reporters are direct in telling their sources that if scoops go to competitors, a price will be paid, and that if moguls appear at the conference of a competitor, like The Wrap, they can expect to be spanked. The site and its alerts are on the smartphones of most industry executives because Deadline Hollywood covers the industry’s every wiggle fast and ferociously.

As one who sometimes wore out her welcome in mainstream media — she has worked at The Associated Press, Newsweek, The Los Angeles Times and New York Magazine — Ms. Finke found her métier on the Web, where sourcing standards are often thin or nonexistent and the prosecution of journalism is a far less mannered affair.

Ms. Finke’s site was bought four years ago with a great deal of fanfare by Jay Penske, a budding media mogul by way of auto racing.

Mr. Penske, who was eager to add heat and gravitas to a group of marginal entertainment assets, walked into the deal with eyes wide open and has been rewarded with a site that gets significant traffic and advertisements. But he has paid dearly for it, spending a great deal of time trying to sooth Ms. Finke or the targets she has maimed.

Deadline’s dominance over the traditional trade outlets was threatened in 2010 after Janice Min, a New York magazine veteran and longtime editor of Us Weekly, took over another competitor, The Hollywood Reporter. To supplement the publication’s Web site, Ms. Min began producing a visually lush weekly magazine that was very well received. Web traffic and advertising have soared in part because Ms. Min produces much more consumer-oriented entertainment coverage.

In an effort to compete, Mr. Penske bought Variety last year, and what had been a strained relationship between Ms. Finke and Mr. Penske broke out into a very public war. Ms. Finke said Mr. Penske had promised to let her supervise the rebirth of the deteriorating Variety brand, but instead froze her out.

She has been complaining bitterly and sometimes publicly since, including saying in print that Mr. Penske had lied to her. Her frenzy and Mr. Penske’s fatigue in managing same are well-known, but the feud gained visibility because Ms. Finke’s contract, which runs until 2016, allows her an escape that will arrive in 2014. No one knows what the mercurial Ms. Finke might do — clearly not Ms. Waxman, not her boss, and maybe not even Ms. Finke herself.


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Thursday, August 9, 2012

20% of U.S. Women Uninsured in 2010, Up From 15% in 2000: Report

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By Steven Reinberg
HealthDay Reporter

FRIDAY, July 13 (HealthDay News) -- Twenty percent of American women had no health insurance in 2010, up from 15 percent in 2000, a new report reveals.

In addition to the nearly 19 million uninsured women, another 17 million women were underinsured in 2010, according to the report, released Friday by the Commonwealth Fund. The fund is a private foundation that seeks to promote improved health care, especially for low-income people, the uninsured, minority Americans, children and the elderly.

The report also compared insurance coverage for U.S. women to women in 10 other industrialized countries: Australia, Canada, France, Germany, the Netherlands, New Zealand, Norway, Sweden, Switzerland and the United Kingdom, all of which have universal health coverage.

While uninsured women in the United States were likely to have problems paying medical bills and getting health care, many insured American women also face these problems, compared with women in other countries, the study found.

Other highlights of the report include:

U.S. women had problems paying medical bills at double the rate of women in any other country studied. In the United States, 26 percent of women had medical bill problems, compared with 13 percent in Australia, 12 percent in France, and 4 percent in Germany. 39 percent of American women spent $1,000 or more in out-of-pocket medical costs during 2009-2010, compared with 24 percent of women in Switzerland, 1 percent in Sweden, and 0 percent in the United Kingdom. 43 percent of U.S. women went without recommended care, didn't see a doctor when they were sick, or didn't fill prescriptions because of cost, compared with 28 percent in Germany and Australia, 8 percent in the Netherlands, and 7 percent in the United Kingdom. Only 52 percent of American women were sure they could afford health care if they became seriously ill, compared with 91 percent of women in the United Kingdom, 77 percent in the Netherlands and 76 percent in Switzerland.

For uninsured women the problems were worse, according to the report, titled "Oceans Apart: The Higher Health Costs of Women in the U.S. Compared to Other Nations, and How Reform Is Helping."

51 percent of uninsured U.S. women had a problem paying medical bills. 77 percent went without needed health care due to costs, more than double the rates of women in other countries.

The report also found insurance differences in the United States among states.

For example, 30 percent of women in Texas were uninsured, compared with 5 percent in Massachusetts, which has a universal health insurance law similar to the Affordable Care Act, the controversial health-reform legislation signed into law in 2010 by President Barack Obama.

Many of these problems will be solved when the Affordable Care Act is fully implemented, the study authors said.

"With the Supreme Court upholding the constitutionality of the Affordable Care Act, the nation is moving forward on ensuring access to high-quality care for all Americans," Karen Davis, president of the Commonwealth Fund, said during a Thursday news conference.

Once the Affordable Care Act is fully implemented in 2014, the rate of uninsured women will drop from 20 percent to 8 percent, the study authors contended.

Under the Act, women can already get preventive care with no co-pay or deductible for services such as screenings for cervical, breast and colon cancer, cholesterol checks, and osteoporosis and chlamydia screenings. And insurance companies cannot deny coverage because of a preexisting condition, the study authors added.

The law will also prevent insurance companies from charging women higher premiums because of their gender or health.

Dr. Bradley Flansbaum, director of Hospitalist Services at Lenox Hill Hospital in New York City, said "the Affordable Care Act fills in the gaps for women's services."

There are disparities in women's health care in coverage and premium costs, he noted.

"It's almost considered that having an extra X chromosome is considered a disability," Flansbaum said. "The Affordable Care Act levels the playing field."

Because not all states are going to increase Medicaid benefits as outlined in the law, there will still be gaps in coverage for women on Medicaid in some states, he added.

The new report is not without critics.

They include Greg Scandlen, director of the Health Benefits Group Inc., which offers health insurance and life insurance to individuals and groups. "This report is a wonderful example of how you can prove anything if you cherry-pick the data carefully enough," he said.

Women aren't disadvantaged when it comes to health insurance, Scandlen said, adding, "In fact, women are far more likely to be covered than are men at nearly every age."

There are sex-based differences in all insurance markets, Scandlen said. "Women pay more for health insurance than men because they consume far more services than men. In the life and auto insurance markets, women pay far less than men because they drive safer and live longer," he said.

By looking at health care in other countries, Scandlen said, the report didn't take into account long wait times for care and the rationing of care in other nations.

"The Affordable Care Act may very well remove price obstacles to care, although that remains to be seen," he said. "But if it floods the system with new patients without increasing the supply of providers, it may result in less actual care for everyone."

MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCES: Bradley Flansbaum, D.O., M.P.H., director, Hospitalist Services, Lenox Hill Hospital, New York City; Greg Scandlen, director, Health Benefits Group; July 12, 2012, press conference with: Karen Davis, president, The Commonwealth Fund; July 13, 2012, report, Oceans Apart: The Higher Health Costs of Women in the U.S. Compared to Other Nations, and How Reform Is Helping



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Thursday, June 21, 2012

Report: Last fugitive nabbed in '95 Japan gassing

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TOKYO (AP) — Japanese police Friday arrested the last fugitive suspected in a doomsday cult's deadly nerve gas attack on Tokyo subways 17 years ago, media reports said.

Katsuya Takahashi, 54, a former member of Aum Shinrikyo cult, was arrested on suspicion of murder after being spotted at a comic book cafe in downtown Tokyo, Japan's public broadcaster NHK said. A cafe employee had recognized him and called police.

Takahashi admitted who he was when approached by the police at the cafe, NHK said.

TV footage showed a huge crowd outside the shop, trying to catch a glimpse of the last cult fugitive. NHK showed a thin, bespectacled Takahashi being pushed into a police car.

His appearance had changed over years — in particular, his trademark bushy eyebrows have become much thinner. So police had to wait while his fingerprints were verified. He was arrested after being taken to a nearby police station, then transferred to Tokyo police headquarters for interrogation, reports said.

Takahashi, who had been cult guru Shoko Asahara's bodyguard, was on Japan's most wanted list for his suspected role in the sarin gas attack on Tokyo subways, which killed 13 people and injured more than 6,000.

Takahashi's trail had been cold for years, but it heated up after another fugitive from the cult was arrested June 3.

Since then, thousands of officers were mobilized across the Tokyo area, handing out fresh photos of Takahashi and monitoring transportation hubs to keep him from escaping the capital.

A security camera last week showed Takahashi trying to withdraw money from a bank shortly after other fugitive was arrested. Police believe he had been hiding in the Tokyo area under a false name. Local media have reported that he was working at a construction company, where he was known as a quiet and anti-social person who always wore a surgical mask.

Aum Shinrikyo had amassed an arsenal of chemical, biological and conventional weapons in anticipation of an apocalyptic showdown with the government. Nearly 200 of its members have been convicted in the 1995 attack and dozens of other crimes. Thirteen, including Asahara, are on death row.

Makoto Hirata, charged in a 1995 cult-related kidnapping-murder as well as the subway attack, surrendered to police on New Year's Eve, stunning the nation. The second-to-last fugitive, Naoko Kikuchi, 40, was arrested on June 3. She had been accused of helping produce the sarin the group released on the subway.

The cult, split into two groups — each renamed Aleph and the Circle of Rainbow Light — once had 10,000 members in Japan and claimed another 30,000 in Russia. It still has hundreds of members. The cult is under police surveillance and its current leaders have publicly disavowed Asahara.


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Saturday, June 2, 2012

When gender matters: Restless legs syndrome. Report of the “RLS and woman” workshop endorsed by the European RLS Study Group

Mauro Manconia, Corresponding author contact information, E-mail the corresponding author, Jan Ulfbergb, Klaus Bergerc, Imad Ghorayebd, Jan Wesströme, Stephany Fuldaf, Richard P. Alleng, Thomas Pollmächerf, ha Sleep and Epilepsy Center, Neurocenter (EOC) of Southern Switzerland, Civic Hospital, Lugano, Via Tesserete 46, 6900 Lugano, Switzerlandb Department of Medicine, Uppsala University, Uppsala, Swedenc Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germanyd Clinical Neurophysiology Department, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux cedex, Francee Center for Clinical Research Dalarna, Department of Women's and Children's Health, Uppsala University, Swedenf Max Planck Institute of Psychiatry, Munich, Germanyg Center of Mental Health, Klinikum Ingolstadt, Ingolstadt, Germanyh Department of Neurology, Johns Hopkins University, Bayview Medical Center, Baltimore, MD, USAReceived 13 May 2011. Revised 30 August 2011. Accepted 30 August 2011. Available online 9 November 2011.View full text Sleep is an essential human behavior that shows prominent gender differences. Disturbed sleep, in particular, is much more prevalent in females than males. Restless legs syndrome (RLS) as one cause of disturbed sleep was observed to be somewhat more common among women than men in Ekbom's 1945 seminal series of clinical cases with the disease. He, however, reported this gender difference mainly for those with more severe symptoms. Since then numerous studies have reported that women are affected by RLS about twice as often as males for mild as well as moderate to severe RLS. The present review focuses on RLS in females from the perspectives of both epidemiology and pathophysiology. RLS will generally become worse or might appear for the first time during pregnancy. Parity increases the risk of RLS later in life suggesting that pregnancy is a specific behavioral risk factor for developing RLS. Some evidence suggests that dysfunction in iron metabolism and high estrogen levels might contribute to RLS during pregnancy. But, menopause does not lower the incidence of RLS nor does hormone replacement therapy lead to an increase, suggesting a quite complex uncertain role of hormones in the pathophysiology of RLS. Therefore, further, preferably longitudinal studies are needed to unravel the factors causing RLS in women. These studies should include genetic, clinical and polysomnographic variables, as well as hormonal measures and variables assessing iron metabolism.

prs.rt("abs_end");Restless legs syndrome; Gender; Female; Sleep; Insomnia; Pregnancy; Estrogens; Menopause; Quality of life

Figures and tables from this article:

Fig. 1. Epidemiological results on RLS and pregnancy. Histograms show the prevalence trend of RLS in a group of 606 women surveyed at the end of pregnancy. In the period before pregnancy, 60 women already experienced RLS symptoms in their life (in a non pregnancy period) and were classified as “pre-existing RLS”. The remaining 546 women had never experienced RLS symptoms before and were classified as “healthy”. During the first assessed pregnancy (2nd histogram) 101 women, out of the 546 “healthy” ones, developed a transient RLS form strictly related to the pregnancy and were classified as “pregnancy-related RLS”. All these 101 women with a new form of pregnancy-related RLS form, except 6 women, recovered after delivery (3rd histogram). Fifty nine of the same pregnancy-related RLS group suffered again RLS symptoms during a further following pregnancy. After a mean follow up of 7 years, 25 out of the 101 women who experienced the symptoms during the first pregnancy (pregnancy-related RLS group) developed a chronic apparently idiopathic RLS form even out of pregnancy. Elaborated data from the study of Cesnik et al.37

View Within ArticleFig. 2. Prevalence of RLS among women in two age groups and according to number of children born in the German general practioner study.43

View Within ArticleFig. 3. Median serum ferritin by age for major USA gender and population groups.

View Within ArticleFig. 4. Prevalence of clinically significant RLS by gender and age from large European and United States population-based samples. (Slightly modified from Allen et al).21

View Within ArticleTable 1. Studies on the prevalence of RLS performed in random samples of the general population of different countries, using the IRLSSG criteria to assess the diagnosis.

View table in articleView Within ArticleTable 2. Epidemiological studies published in literature on RLS prevalence that included an assessment on the quality of life.

View table in articleAbbreviations: EQ-5D VAS, visual analogue scale score for the EQ-5D, a quality of life questionnaire developed by the EuroQoL Group; HRQoL, health related quality of life; MCS, mental component score of the SF-36; RLS, restless legs syndrome; PCS, physical component score of the SF-36; SF-36, SF-12, short form health survey.

View Within ArticleTable 3. Studies exploring the role of estrogens in RLS.

View table in articleAbbreviations: AC, active controlled; CO, crossover; DB, double blind; HRT, hormone replacement therapy; IQR, interquartile range; PC, placebo controlled; PG, parallel group; PLM, periodic leg movements; R, randomized; SD, standard deviation.

View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.

prs.rt('data_end');

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When gender matters: Restless legs syndrome. Report of the “RLS and woman” workshop endorsed by the European RLS Study Group

Mauro Manconia, Corresponding author contact information, E-mail the corresponding author, Jan Ulfbergb, Klaus Bergerc, Imad Ghorayebd, Jan Wesströme, Stephany Fuldaf, Richard P. Alleng, Thomas Pollmächerf, ha Sleep and Epilepsy Center, Neurocenter (EOC) of Southern Switzerland, Civic Hospital, Lugano, Via Tesserete 46, 6900 Lugano, Switzerlandb Department of Medicine, Uppsala University, Uppsala, Swedenc Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germanyd Clinical Neurophysiology Department, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux cedex, Francee Center for Clinical Research Dalarna, Department of Women's and Children's Health, Uppsala University, Swedenf Max Planck Institute of Psychiatry, Munich, Germanyg Center of Mental Health, Klinikum Ingolstadt, Ingolstadt, Germanyh Department of Neurology, Johns Hopkins University, Bayview Medical Center, Baltimore, MD, USAReceived 13 May 2011. Revised 30 August 2011. Accepted 30 August 2011. Available online 9 November 2011.View full text Sleep is an essential human behavior that shows prominent gender differences. Disturbed sleep, in particular, is much more prevalent in females than males. Restless legs syndrome (RLS) as one cause of disturbed sleep was observed to be somewhat more common among women than men in Ekbom's 1945 seminal series of clinical cases with the disease. He, however, reported this gender difference mainly for those with more severe symptoms. Since then numerous studies have reported that women are affected by RLS about twice as often as males for mild as well as moderate to severe RLS. The present review focuses on RLS in females from the perspectives of both epidemiology and pathophysiology. RLS will generally become worse or might appear for the first time during pregnancy. Parity increases the risk of RLS later in life suggesting that pregnancy is a specific behavioral risk factor for developing RLS. Some evidence suggests that dysfunction in iron metabolism and high estrogen levels might contribute to RLS during pregnancy. But, menopause does not lower the incidence of RLS nor does hormone replacement therapy lead to an increase, suggesting a quite complex uncertain role of hormones in the pathophysiology of RLS. Therefore, further, preferably longitudinal studies are needed to unravel the factors causing RLS in women. These studies should include genetic, clinical and polysomnographic variables, as well as hormonal measures and variables assessing iron metabolism.

prs.rt("abs_end");Restless legs syndrome; Gender; Female; Sleep; Insomnia; Pregnancy; Estrogens; Menopause; Quality of life

Figures and tables from this article:

Fig. 1. Epidemiological results on RLS and pregnancy. Histograms show the prevalence trend of RLS in a group of 606 women surveyed at the end of pregnancy. In the period before pregnancy, 60 women already experienced RLS symptoms in their life (in a non pregnancy period) and were classified as “pre-existing RLS”. The remaining 546 women had never experienced RLS symptoms before and were classified as “healthy”. During the first assessed pregnancy (2nd histogram) 101 women, out of the 546 “healthy” ones, developed a transient RLS form strictly related to the pregnancy and were classified as “pregnancy-related RLS”. All these 101 women with a new form of pregnancy-related RLS form, except 6 women, recovered after delivery (3rd histogram). Fifty nine of the same pregnancy-related RLS group suffered again RLS symptoms during a further following pregnancy. After a mean follow up of 7 years, 25 out of the 101 women who experienced the symptoms during the first pregnancy (pregnancy-related RLS group) developed a chronic apparently idiopathic RLS form even out of pregnancy. Elaborated data from the study of Cesnik et al.37

View Within ArticleFig. 2. Prevalence of RLS among women in two age groups and according to number of children born in the German general practioner study.43

View Within ArticleFig. 3. Median serum ferritin by age for major USA gender and population groups.

View Within ArticleFig. 4. Prevalence of clinically significant RLS by gender and age from large European and United States population-based samples. (Slightly modified from Allen et al).21

View Within ArticleTable 1. Studies on the prevalence of RLS performed in random samples of the general population of different countries, using the IRLSSG criteria to assess the diagnosis.

View table in articleView Within ArticleTable 2. Epidemiological studies published in literature on RLS prevalence that included an assessment on the quality of life.

View table in articleAbbreviations: EQ-5D VAS, visual analogue scale score for the EQ-5D, a quality of life questionnaire developed by the EuroQoL Group; HRQoL, health related quality of life; MCS, mental component score of the SF-36; RLS, restless legs syndrome; PCS, physical component score of the SF-36; SF-36, SF-12, short form health survey.

View Within ArticleTable 3. Studies exploring the role of estrogens in RLS.

View table in articleAbbreviations: AC, active controlled; CO, crossover; DB, double blind; HRT, hormone replacement therapy; IQR, interquartile range; PC, placebo controlled; PG, parallel group; PLM, periodic leg movements; R, randomized; SD, standard deviation.

View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.

prs.rt('data_end');

View the original article here

When gender matters: Restless legs syndrome. Report of the “RLS and woman” workshop endorsed by the European RLS Study Group

Mauro Manconia, Corresponding author contact information, E-mail the corresponding author, Jan Ulfbergb, Klaus Bergerc, Imad Ghorayebd, Jan Wesströme, Stephany Fuldaf, Richard P. Alleng, Thomas Pollmächerf, ha Sleep and Epilepsy Center, Neurocenter (EOC) of Southern Switzerland, Civic Hospital, Lugano, Via Tesserete 46, 6900 Lugano, Switzerlandb Department of Medicine, Uppsala University, Uppsala, Swedenc Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germanyd Clinical Neurophysiology Department, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux cedex, Francee Center for Clinical Research Dalarna, Department of Women's and Children's Health, Uppsala University, Swedenf Max Planck Institute of Psychiatry, Munich, Germanyg Center of Mental Health, Klinikum Ingolstadt, Ingolstadt, Germanyh Department of Neurology, Johns Hopkins University, Bayview Medical Center, Baltimore, MD, USAReceived 13 May 2011. Revised 30 August 2011. Accepted 30 August 2011. Available online 9 November 2011.View full text Sleep is an essential human behavior that shows prominent gender differences. Disturbed sleep, in particular, is much more prevalent in females than males. Restless legs syndrome (RLS) as one cause of disturbed sleep was observed to be somewhat more common among women than men in Ekbom's 1945 seminal series of clinical cases with the disease. He, however, reported this gender difference mainly for those with more severe symptoms. Since then numerous studies have reported that women are affected by RLS about twice as often as males for mild as well as moderate to severe RLS. The present review focuses on RLS in females from the perspectives of both epidemiology and pathophysiology. RLS will generally become worse or might appear for the first time during pregnancy. Parity increases the risk of RLS later in life suggesting that pregnancy is a specific behavioral risk factor for developing RLS. Some evidence suggests that dysfunction in iron metabolism and high estrogen levels might contribute to RLS during pregnancy. But, menopause does not lower the incidence of RLS nor does hormone replacement therapy lead to an increase, suggesting a quite complex uncertain role of hormones in the pathophysiology of RLS. Therefore, further, preferably longitudinal studies are needed to unravel the factors causing RLS in women. These studies should include genetic, clinical and polysomnographic variables, as well as hormonal measures and variables assessing iron metabolism.

prs.rt("abs_end");Restless legs syndrome; Gender; Female; Sleep; Insomnia; Pregnancy; Estrogens; Menopause; Quality of life

Figures and tables from this article:

Fig. 1. Epidemiological results on RLS and pregnancy. Histograms show the prevalence trend of RLS in a group of 606 women surveyed at the end of pregnancy. In the period before pregnancy, 60 women already experienced RLS symptoms in their life (in a non pregnancy period) and were classified as “pre-existing RLS”. The remaining 546 women had never experienced RLS symptoms before and were classified as “healthy”. During the first assessed pregnancy (2nd histogram) 101 women, out of the 546 “healthy” ones, developed a transient RLS form strictly related to the pregnancy and were classified as “pregnancy-related RLS”. All these 101 women with a new form of pregnancy-related RLS form, except 6 women, recovered after delivery (3rd histogram). Fifty nine of the same pregnancy-related RLS group suffered again RLS symptoms during a further following pregnancy. After a mean follow up of 7 years, 25 out of the 101 women who experienced the symptoms during the first pregnancy (pregnancy-related RLS group) developed a chronic apparently idiopathic RLS form even out of pregnancy. Elaborated data from the study of Cesnik et al.37

View Within ArticleFig. 2. Prevalence of RLS among women in two age groups and according to number of children born in the German general practioner study.43

View Within ArticleFig. 3. Median serum ferritin by age for major USA gender and population groups.

View Within ArticleFig. 4. Prevalence of clinically significant RLS by gender and age from large European and United States population-based samples. (Slightly modified from Allen et al).21

View Within ArticleTable 1. Studies on the prevalence of RLS performed in random samples of the general population of different countries, using the IRLSSG criteria to assess the diagnosis.

View table in articleView Within ArticleTable 2. Epidemiological studies published in literature on RLS prevalence that included an assessment on the quality of life.

View table in articleAbbreviations: EQ-5D VAS, visual analogue scale score for the EQ-5D, a quality of life questionnaire developed by the EuroQoL Group; HRQoL, health related quality of life; MCS, mental component score of the SF-36; RLS, restless legs syndrome; PCS, physical component score of the SF-36; SF-36, SF-12, short form health survey.

View Within ArticleTable 3. Studies exploring the role of estrogens in RLS.

View table in articleAbbreviations: AC, active controlled; CO, crossover; DB, double blind; HRT, hormone replacement therapy; IQR, interquartile range; PC, placebo controlled; PG, parallel group; PLM, periodic leg movements; R, randomized; SD, standard deviation.

View Within ArticleCopyright © 2011 Elsevier Ltd. All rights reserved.

prs.rt('data_end');

View the original article here

Friday, May 25, 2012

Mutual Funds Report: First Quarter

AppId is over the quota AppId is over the quota A second consecutive quarter of eye-popping gains for stocks hasn’t convinced much of the investor world that happy days are here again.

The rising market in the first quarter was built on technology and consumer stocks, not the safe, income-producing shares that led it higher at the start of 2011.


 

Monday, May 21, 2012

Mutual Funds Report: First Quarter

AppId is over the quota AppId is over the quota A second consecutive quarter of eye-popping gains for stocks hasn’t convinced much of the investor world that happy days are here again.

The rising market in the first quarter was built on technology and consumer stocks, not the safe, income-producing shares that led it higher at the start of 2011.


 

Saturday, May 19, 2012

Mutual Funds Report: First Quarter





AppId is over the quota AppId is over the quota A second consecutive quarter of eye-popping gains for stocks hasn’t convinced much of the investor world that happy days are here again.

The rising market in the first quarter was built on technology and consumer stocks, not the safe, income-producing shares that led it higher at the start of 2011.

Monday, May 14, 2012

Battling depression with "battery-powered brains" - CNN report on deep brain stimulation (DBS)

AppId is over the quota AppId is over the quota CNN reports on treating severe depression with electrodes inside the brain:

The procedure -- called deep brain stimulation, or DBS -- targets a small brain structure known as Area 25, the "ringleader" for the brain circuits that control our moods.


Area 25 is relatively overactive in depressed patients. One hypothesis is that in patients who do not improve with treatments for depression, Area 25 is somehow stuck in overdrive.


DBS had been used since 1997 as a treatment for movement disorders, including essential tremor, Parkinson's disease and dystonia.


References:


Treating depression with electrodes inside the brain. CNN, 2012.


 

Battling depression with "battery-powered brains" - CNN report on deep brain stimulation (DBS)

AppId is over the quota AppId is over the quota CNN reports on treating severe depression with electrodes inside the brain:

The procedure -- called deep brain stimulation, or DBS -- targets a small brain structure known as Area 25, the "ringleader" for the brain circuits that control our moods.


Area 25 is relatively overactive in depressed patients. One hypothesis is that in patients who do not improve with treatments for depression, Area 25 is somehow stuck in overdrive.


DBS had been used since 1997 as a treatment for movement disorders, including essential tremor, Parkinson's disease and dystonia.


References:


Treating depression with electrodes inside the brain. CNN, 2012.


 

Battling depression with "battery-powered brains" - CNN report on deep brain stimulation (DBS)

AppId is over the quota AppId is over the quota CNN reports on treating severe depression with electrodes inside the brain:

The procedure -- called deep brain stimulation, or DBS -- targets a small brain structure known as Area 25, the "ringleader" for the brain circuits that control our moods.


Area 25 is relatively overactive in depressed patients. One hypothesis is that in patients who do not improve with treatments for depression, Area 25 is somehow stuck in overdrive.


DBS had been used since 1997 as a treatment for movement disorders, including essential tremor, Parkinson's disease and dystonia.


References:


Treating depression with electrodes inside the brain. CNN, 2012.